15 Unexpected Side Effects Of Ashwagandha & Essential Precautions

15 Serious Side Effects Of Ashwagandha & Precautions To Take

Ashwagandha is an ancient adaptogenic herb revered in Ayurvedic medicine for its purported health benefits, including stress reduction, improved mood, and enhanced energy. However, despite its popularity, not all users are aware of the potential risks associated with this supplement. While generally safe when used appropriately for short periods, improper or excessive consumption may lead to serious side effects, particularly in vulnerable populations. This article highlights the unexpected side effects of ashwagandha, populations at risk, and key precautions to ensure safe use.

Table of Contents

• Ashwagandha Overview
• 15 Unexpected Side Effects of Ashwagandha
• Drug Interactions
• Who Should Avoid Ashwagandha?
• Precautions To Take
• Frequently Asked Questions (FAQs)

What is Ashwagandha?

Ashwagandha (Withania somnifera), also known as Indian Ginseng, is an herbal remedy traditionally used in Ayurvedic medicine for its adaptogenic and restorative properties. Its widespread use has rapidly increased globally due to claims of supporting stress management, immunity, and overall well-being . While many people turn to ashwagandha for these benefits, understanding its potential dangers is essential before adding it to your regimen.

15 Unexpected Side Effects of Ashwagandha

Although generally safe for short-term use, ashwagandha may trigger adverse reactions—especially when consumed in high doses or for prolonged periods. Below are 15 potential side effects to be aware of:

• Gastrointestinal Distress
  • Common symptoms include nausea, diarrhea, upset stomach, abdominal discomfort, and vomiting—especially at higher doses or with prolonged use .
  • Some users report increased acidity and indigestion.
• Allergic Reactions
  • Ashwagandha belongs to the Solanaceae family; people allergic to tomatoes, potatoes, or eggplant may react similarly to this herb .
  • Reactions may include rashes, itching, swelling, or difficulty breathing. Seek medical attention immediately if symptoms appear.
• Liver Toxicity
  • Rare cases of liver injury, including jaundice, pruritus, lethargy, and even severe liver failure, have been reported—sometimes requiring transplantation .
  • Those with pre-existing liver disease are particularly at risk .
• Lowered Blood Pressure
  • Ashwagandha may cause sudden fluctuations or drops in blood pressure, especially in people taking antihypertensive medications .
• Altered Blood Sugar Levels
  • May cause unexpected changes or drops in blood glucose, interacting with anti-diabetic drugs .
• Thyroid Hormone Changes
  • Can increase thyroid hormone levels—problematic for individuals with thyroid disorders or those on thyroid medications .
• Excessive Sedation, Drowsiness & Sleepiness
  • Its sedative effect may worsen lethargy, especially in combination with sleep meds, anti-anxiety drugs, or alcohol .
  • Reports exist of vivid dreams and increased somnolence.
• Drug Interactions
  • Can potentiate effects of benzodiazepines, sedatives, immunosuppressants, blood thinners, and thyroid medications (see table below) .
• Risk of Miscarriage During Pregnancy
  • Ashwagandha is likely unsafe during pregnancy and may induce miscarriages; pregnant women should avoid use entirely .
• Not Safe for Breastfeeding Women
  • Insufficient data exist on safety during lactation; it’s advised to abstain .
• Worsening of Autoimmune Disorders
  • Stimulates immune activity, potentially exacerbating autoimmune diseases like lupus, rheumatoid arthritis, and multiple sclerosis .
• Risk for Newborns & Infants
  • Adverse effects are unknown; avoid herbal medication in this population .
• Central Nervous System Depression
  • May slow nervous system function, compounding anesthesia and post-operative drug effects; discontinue use two weeks before surgery .
• Hypersensitivity to Plant-Based Supplements
  • Individuals with a history of plant allergies should exercise caution; perform allergy testing beforehand .
• Impaired Digestion/Absorption
  • Can disrupt gut function in sensitive individuals, especially with chronic use or high doses .

Summary Table: Common Ashwagandha Side Effects & Risk Groups

Drug Interactions With Ashwagandha

Ashwagandha’s potent biochemical activity means it can interact with various pharmaceutical agents, sometimes dangerously. Common interactions include:

• Alcohol: May amplify sedative effects, leading to excessive drowsiness and risk of coma .
• Benzodiazepines and Sleeping Pills: Can intensify sedation, raising risk of impaired cognition or CNS depression .
• Immunosuppressants: Use may reduce drug efficacy or increase immune system activation .
• Blood Pressure & Blood-Thinning Medications: May cause sudden blood pressure changes or increased blood thinning, leading to complications .
• Thyroid Medications: May increase thyroid hormone levels, risking hyperthyroidism .
• Diabetes Medications: May lower blood sugar levels excessively .

Note: Always consult a healthcare provider before combining ashwagandha with prescribed drugs.

Who Should Avoid Ashwagandha?

• Pregnant women (risk of miscarriage)
• Breastfeeding women (insufficient safety data)
• Newborns and infants (unknown safety risks)
• People with autoimmune disorders (e.g., lupus, MS, RA)
• Individuals with liver disease (potential liver toxicity)
• Patients scheduled for surgery (risk of CNS depression)
• Those on thyroid, blood sugar, blood pressure, immunosuppressant, or sedative medications (risk of adverse drug interactions)
• Individuals with known plant or Solanaceae allergies
• Anyone experiencing digestive problems after use

Precautions To Take with Ashwagandha

1. Always Consult Your Doctor: Especially if you have an underlying health condition or take prescription meds.
2. Start With Small Doses: To test tolerance and minimize digestive upset.
3. Take with Food and Water: Helps reduce likelihood of stomach irritation.
4. Discontinue Immediately if Adverse Symptoms Appear: Especially with signs of allergy, jaundice, persistent nausea, vomiting, or lethargy.
5. Avoid During Pregnancy, Breastfeeding, and in Children: Safety cannot be guaranteed for these groups.
6. Stop Use Before Surgery: Cease taking at least 2 weeks prior to scheduled procedures to avoid CNS complications.
7. Perform Allergy Tests: If you have a history of plant allergies, consider testing before extended use.
8. Monitor for Drug Interactions: Check for potential medication conflicts using professional guidance.
9. Use Only Trusted Supplements: Source from reliable brands to avoid contamination or adulteration.
10. Limit Duration and Dosage: Long-term and excessive intake increases risk of side effects.

Frequently Asked Questions (FAQs)

Q1: Can ashwagandha cause allergies?

Yes, although rare, ashwagandha may trigger allergies—especially in people sensitive to plants in the Solanaceae family. Symptoms can include rashes, swelling, and respiratory distress .

Q2: Is ashwagandha safe for pregnant or breastfeeding women?

No, ashwagandha is considered unsafe for pregnant women due to risk of miscarriage. Safety during breastfeeding is unknown—best to avoid .

Q3: Can ashwagandha interact with prescription medications?

Yes. Notably, the herb can interact with thyroid medicines, diabetes drugs, sedatives, immunosuppressants, blood thinners, and blood pressure medications. Always consult your doctor before use .

Q4: What are signs of liver toxicity from ashwagandha?

Symptoms may include jaundice, dark urine, pruritus, abdominal pain, and lethargy. Seek medical help if these occur—especially in individuals with pre-existing liver issues .

Q5: How can I minimize digestive side effects?

Start with a low dose, take with food and water, and avoid use on an empty stomach. Monitor your body’s response and discontinue if persistent issues develop .

Q6: Does ashwagandha cause drowsiness?

Yes, drowsiness and sedation are common side effects. It may also enhance the effect of other sedatives, including alcohol and sleeping pills .

Q7: Is long-term use of ashwagandha safe?

No comprehensive studies confirm the safety of long-term use; monitoring for side effects is essential, and extended usage should only occur under medical supervision .

Conclusion

Though ashwagandha offers many potential health benefits, its improper or unsuitable use can lead to significant health risks in certain populations. Understanding these unexpected side effects, consulting healthcare professionals, and using caution when supplementing are crucial steps toward safe and effective herbal care.

Author

Sneha TeteBeauty & Lifestyle Writer

 

Sneha is a relationships and lifestyle writer with a strong foundation in applied linguistics and certified training in relationship coaching. She brings over five years of writing experience to thebridalbox, crafting thoughtful, research-driven content that empowers readers to build healthier relationships, boost emotional well-being, and embrace holistic living.

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