4 Unexpected Side Effects Of Mulberry You Should Know

Mulberries are celebrated for their naturally sweet taste and impressive antioxidant content, making them a popular choice in diets around the world. However, while mulberries offer many health benefits, it is essential to be aware of their potential side effects, especially when consumed in excess or by people with specific health conditions.

Table of Contents

• What Is Mulberry?
• Key Side Effects of Mulberry
  • 1. Low Blood Sugar Levels (Hypoglycemia)
  • 2. Gastrointestinal Discomfort
  • 3. Interference With Carbohydrate Absorption
  • 4. Potential Kidney Effects and Internal Bleeding
  • Other Possible Side Effects
• Mulberry Drug Interactions
• Who Should Avoid Mulberries?
• When To See a Doctor
• Frequently Asked Questions

What Is Mulberry?

Mulberry refers to the fruit of trees in the Morus genus, part of the Moraceae family. The fruit can be white, red, or black, corresponding to the main species: Morus alba (white mulberry), Morus rubra (red mulberry), and Morus nigra (black mulberry). All varieties are rich in vitamins and minerals, notably vitamin C, vitamin K, iron, potassium, and dietary fiber. Traditionally, both the fruit and leaves have been used in medicine, particularly in Asian cultures, for their reputed health-promoting properties.

Mulberries are enjoyed fresh, dried, and processed into jams, juices, and other products. However, consuming large amounts of mulberry or its extracts can trigger adverse effects in some individuals.

Key Side Effects of Mulberry

1. Low Blood Sugar Levels (Hypoglycemia)

Mulberries, particularly the leaves, have been shown to lower blood glucose levels. While this property can be beneficial for people seeking to control their blood sugar, it can also lead to problems such as:

• Hypoglycemia (excessively low blood sugar), especially in people who already take medications for diabetes or struggle with fluctuating sugar levels.
• Symptoms may include dizziness, weakness, shakiness, sweating, confusion, rapid heartbeat, or, in severe cases, loss of consciousness.
• These effects have been documented both after consuming the fruit and after taking mulberry leaf tablets.

Note: People with diabetes or on blood sugar-lowering medications should be especially cautious.

2. Gastrointestinal Discomfort

One of the most common side effects reported with mulberry products is digestive system irritation. This may include:

• Indigestion
• Nausea and vomiting
• Diarrhea
• Bloating and abdominal discomfort
• Constipation (rarely)

Several clinical studies observed these effects. For example, a trial involving mulberry leaf tablets in patients with high cholesterol found that more than 25% developed mild diarrhea or dizziness. Mulberry’s latex (a milky white sap present in stems and unripe fruit) may especially cause gastrointestinal upset and should be avoided due to its mild toxicity.

3. Interference With Carbohydrate Absorption

Mulberry has the ability to inhibit carbohydrate digestion, meaning it slows or reduces the absorption of sugars from food. While this may help some manage blood sugar or lose weight, excessive long-term use can have unintended effects:

• Can result in low energy levels, fatigue, and mood changes, especially for those who require stable carbohydrate intake (such as athletes or people with metabolic concerns).
• May aggravate digestive symptoms—gas, cramps, bloating—by allowing more undigested carbohydrates to reach the large intestine.
• Overuse is not recommended for those with digestive disorders or those who eat very little.

4. Potential Kidney Effects and Internal Bleeding

Mulberries contain relatively high levels of potassium. For most healthy individuals, this is harmless, but for those with chronic kidney disease or kidney dysfunction, high potassium can be dangerous, potentially leading to:

• Dehydration: Excess potassium and some compounds in mulberry may increase urine output, causing the body to lose too much water and electrolytes.
• Internal bleeding: Cases are rare, but combined dehydration and altered electrolyte balance may contribute to bleeding issues and poor healing. Caution is particularly warranted with large quantities or concentrated extracts.

Always consult a healthcare provider if you have kidney problems before consuming mulberries or supplements derived from them.

Other Possible Side Effects

• Skin Irritation: The latex from unripe mulberries or certain supplements can cause mild skin rashes or itching.
• Allergic Reactions: Rare, but individuals allergic to fig or similar fruits may also react to mulberries.
• Risk during Pregnancy/Breastfeeding: Lack of reliable safety data; best avoided unless approved by a doctor.
• Risk of Abortion (in high extract doses): Some evidence suggests high levels of certain mulberry extracts can be harmful during pregnancy.

Mulberry Drug Interactions

Mulberry’s effects on the body can alter how certain medications work. Important interactions include:

• Antidiabetic Medications: Because mulberry lowers blood sugar, it can boost the effects of prescription diabetes medications, risking dangerously low blood sugar (hypoglycemia).
• Urate-Lowering Medications: Mulberry may interact with drugs intended to manage gout or lower uric acid.
• Midazolam (Versed): Black mulberry may slow the breakdown of this sedative drug, increasing its effects and potential side effects.
• Surgery: Because mulberry can influence blood sugar levels, people scheduled for surgery should stop use at least 2 weeks in advance to reduce the risk of blood sugar fluctuations.

Who Should Avoid Mulberries?

When To See a Doctor

Contact your healthcare provider promptly if you experience:

• Severe or persistent gastrointestinal symptoms (e.g., diarrhea lasting more than 48 hours, vomiting, or significant bloating)
• Very low blood sugar (extreme fatigue, confusion, fainting, palpitations)
• Signs of allergic reaction: rash, itching, swelling (especially of the face or throat), or difficulty breathing
• Unusual bleeding, bruising, or symptoms suggestive of kidney dysfunction (e.g., swelling, reduced urination)

Infographic: Common Side Effects Of Mulberry

• Suppresses healthy after-meal rise in blood glucose, possibly causing hypoglycemia in sensitive individuals.
• May cause skin irritation with some products or exposure to sap.
• May trigger nausea, indigestion, diarrhea, and bloating.
• Overconsumption for weight loss may negatively affect digestion and carbohydrate absorption.
• High potassium content can be a risk factor for those with kidney conditions.

Frequently Asked Questions (FAQs)

Q1: Is it safe to eat mulberries every day?

For most healthy people, moderate daily consumption is safe. However, excessive intake or concentrated extracts can increase the risk of digestive issues, hypoglycemia, and—if you have kidney problems—dehydration or potassium-related complications. Stick to dietary portions unless otherwise advised by your healthcare provider.

Q2: Can mulberries be harmful if I take diabetes medication?

Yes. Both mulberry fruit and especially the leaves can lower blood glucose. When combined with antidiabetic drugs, this can cause your blood sugar to fall too low. Monitor your blood sugar levels closely and consult your doctor before consuming mulberry products if you use these medications.

Q3: Are there any allergy risks with mulberries?

Mulberries share similar proteins with figs. If you have a known fig allergy, avoid mulberries to prevent allergic reactions. Symptoms may include rash, itching, swelling, or breathing difficulties.

Q4: Is it safe to consume mulberry during pregnancy or breastfeeding?

Because there is insufficient safety data, pregnant and breastfeeding women should avoid mulberry products unless specifically approved by a healthcare provider.

Q5: Can mulberry supplements help with weight loss?

Some studies suggest that mulberry leaf extract may reduce carbohydrate digestion and aid in weight management. However, this effect can also lead to side effects like indigestion, diarrhea, bloating, and excessively low blood sugars. Use any supplement only under medical supervision, and do not substitute it for a balanced diet and exercise.

Additional Tips for Safe Mulberry Consumption

• Always consume mulberries as part of a varied and balanced diet.
• If using supplements, start with small doses to test your tolerance.
• Wash fresh berries thoroughly to remove any residues or allergens.
• Do not ingest unripe fruit or sap.
• Consult your healthcare provider if you have underlying medical conditions or take prescription medications.

Author

Medha DebCommerce Editor

 

Medha Deb is a commerce editor with a master's degree in applied linguistics from the University of Hyderabad, which has allowed her to develop a deep understanding of language and its application in various contexts. She specializes in the areas of beauty, health, and wellness and is committed to ensuring that the content on the website is of the highest quality.

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