The 2016 Mercedes-Benz E-Class stands as a pinnacle of midsize luxury sedans, blending refined performance, advanced technology, and unparalleled comfort. This generation introduced significant updates in powertrains, safety features, and driver assistance systems, making it a compelling choice for executives and enthusiasts alike.
Powertrain Variety and Performance Excellence
The 2016 E-Class offers an impressive array of engines catering to diverse driving preferences, from efficient diesels to high-performance V8s. Base models like the E250 Bluetec diesel achieve exceptional fuel economy at 33 mpg combined (28 city/42 highway), while all-wheel-drive variants maintain strong efficiency at 31 mpg combined. Gasoline options include the E350 with 23 mpg combined and quicker E400 and E550 models matching or exceeding that efficiency despite their power.
Acceleration figures highlight the lineup’s versatility: the E250 reaches 0-60 mph in 7.6 seconds, the E350 in 6.0 seconds (AWD), E550 in 5.0 seconds, and the E63 AMG S sedan blasts to 60 mph in 3.7 seconds. Drivetrain choices include rear-wheel drive for most trims, with 4Matic all-wheel drive standard on wagons and AMG models, biasing 67% power to the rear for sporty dynamics.
| Model | 0-60 mph (sec) | Combined MPG | Drivetrain |
|---|---|---|---|
| E250 Bluetec | 7.6 | 33 | RWD/AWD |
| E350 | 6.0 (AWD) | 23 | RWD/AWD |
| E550 | 5.0 | 23 | RWD |
| E63 AMG S Sedan | 3.7 | N/A | AWD |
Driving Dynamics and Ride Quality
Mercedes engineers prioritized a balance of comfort and control in the 2016 E-Class. Its suspension delivers an exceptionally absorbent ride, absorbing road imperfections while remaining taut for confident handling. Unlike nimbler rivals like the Audi A6, the E-Class emphasizes solidity—a hallmark of Mercedes—with capable cornering that belies its luxury focus.
Owners and reviewers praise its stress-free long-distance cruising, quiet cabin, and mature demeanor. The E63 AMG S variant shifts toward aggression with stiffer tuning, but standard models excel in grand touring.
Interior Luxury and Practicality
Step inside the 2016 E-Class to find a cabin that merges elegance and functionality. A three-tube gauge cluster and analog clock add sophistication, complemented by premium wood veneers and high-quality materials. The steering-column gear selector frees console space, enhancing usability.
Seating is supportive and firm, with multicontour options providing long-haul comfort. Four-door models offer generous rear space rivaling the BMW 5 Series, while two-doors sacrifice some accessibility. Cargo capacity is practical: sedans at 15.9 cu ft, wagons up to 57.4 cu ft with a third-row option, coupes at 13.3 cu ft, and convertibles at 11.5 cu ft.
- Front seats: Highly supportive, especially in sport trims.
- Rear space (sedan): Accommodates adults comfortably.
- Infotainment: Intuitive navigation and audio systems.
Safety Innovations and Crash Ratings
Safety remains a Mercedes cornerstone, with the 2016 E-Class earning four stars overall from NHTSA (four frontal, five side). IIHS awarded \”Good\” ratings in small-overlap frontal, moderate-overlap, side, and roof tests.
Advanced aids include Drive Pilot semi-autonomous tech, enabling highway following up to 130 mph, lane changes, and operation on unmarked roads up to 81 mph—outpacing even pricier S-Class systems.
Technology and Driver Assistance
The E-Class pioneered semi-autonomous driving in 2016, with sensors for adaptive cruise, lane-keeping, and autonomous lane changes. This tech reduces driver fatigue on long trips, positioning Mercedes ahead in luxury innovation.
Standard features encompass a premium COMAND system, while options add luxury like massaging seats and ambient lighting.
Ownership Experience and Reliability
Consumer feedback is overwhelmingly positive, with Kelley Blue Book and Cars.com reviews highlighting luxury feel, handling, acceleration, and compliments on styling. Common praises include fun driving dynamics and premium build; minor gripes involve firm seats or infotainment learning curves.
Warranty covers 4 years/50,000 miles, with MSRP starting around $62,250 excluding destination. Fuel costs average $252/month at typical mileage.
Body Styles and Trim Options
- Sedan: Most popular, balanced size and efficiency.
- Wagon: Massive cargo, optional third row for seven seats.
- Coupe/Convertible: Stylish alternatives with sportier seating.
- AMG Variants: Performance-focused with enhanced power.
Competitor Comparison
| Aspect | 2016 E-Class | BMW 5 Series | Audi A6 |
|---|---|---|---|
| Ride Comfort | Exceptional absorption | Sporty but firm | Balanced |
| Rear Space | Matches BMW | Best in class | Good |
| Fuel Economy (base) | 33 mpg diesel | 25 mpg | 24 mpg |
| 0-60 (top model) | 3.7 sec | 3.9 sec | 4.4 sec |
The E-Class edges rivals in comfort and tech, though BMW leads in rear space and Audi in agility.
Frequently Asked Questions (FAQs)
Is the 2016 E-Class reliable?
Yes, owners report high satisfaction with performance and durability, backed by Mercedes’ warranty.
What is the best engine choice?
E250 Bluetec for efficiency, E350 for balance, E63 AMG for thrill.
How safe is it?
Top IIHS and NHTSA scores, plus pioneering semi-autonomous features.
What’s the cargo space like?
Sedan: 15.9 cu ft; Wagon: up to 57.4 cu ft.
Should I buy used?
Excellent value with proven longevity, per owner reviews.
Final Thoughts on Value
At its 2016 price point, the E-Class delivered unmatched luxury, tech, and versatility. Today, used models offer premium ownership without new-car depreciation, ideal for those seeking refined motoring.
References
- 2016 Mercedes-Benz E-Class Review & Ratings — Edmunds. 2016. https://www.edmunds.com/mercedes-benz/e-class/2016/review/
- Mercedes-Benz E-Class (2016-2023) Review — Top Gear. 2026. https://www.topgear.com/car-reviews/mercedes-benz/e-class-2016-2023
- 2016 Mercedes-Benz E-Class review — WhichCar. 2016. https://www.whichcar.com.au/reviews/2016-mercedes-benz-e-class-review
- 2016 Mercedes-Benz E-class Consumer Reviews — Kelley Blue Book. 2016. https://www.kbb.com/mercedes-benz/e-class/2016/consumer-reviews/
- 2016 Mercedes-Benz E-Class Consumer Reviews — Cars.com. 2016. https://www.cars.com/research/mercedes_benz-e_class-2016/consumer-reviews/

